What is the significance of these two places? The 1860 census shows Elisabeth Turpin (Elizabeth Russell Turpin) as living within the postal area of Lues Well in Anderson County (TN), and the family of James and Jerusa Turpin are found in the postal area of Welcker Mill in Roane County (TN).
Welcker Mill was located at the confluence of East Fork and Main Poplar Creek adjacent to the present-day site of the K-25 Oak Ridge plant on the northeast side. We do not yet know how close James and Jerusa actually lived to the site of the mill and post office.
As far as Lues Well is concerned, the search continues.